The toluene is also known as toluol. Both have the same chemical structure and are benzene derivatives. Toluol is the older name, given by Jons Jokob Berzelius when he managed to isolate the chemical from a tropical Colombian tree. One of the hydrogen atoms in the benzene’s structure is replaced by a -CH3 radical – that the formula of the toluene. Its chemical reactions are far more different than the benzene’s. This is due to its -CH3 radical which makes the toluene more active in chemical reactions. Like benzene the toluol is an aromatic hydrocarbon which is water-insoluble and used as a organic solvent. Let’s take a look at its material safety data sheet.
It can be used as a drug since it has intoxicating properties. Inhaling the toluene can cause severe neurological problems due to its high toxicity. It can also be absorbed through the skin during a dermal contact. Once the toluene is in the blood circulation it can harm all the internal organs – the nervous system, the kidneys, liver, brain e.t.c. In the toluene hazards we can also include ingestion, inhalation, skin contact. According to toluene msds the lethal dose is 50mg/kg.
When pregnant women are exposed to the effects of toluene you should have in mind that the toxic chemical passes through the placental barrier. Therefore it can be found in the maternal milk in human beings. The toluol is teratogenic (can be thew cause of various birth defects) and mutagenic (can cause changes in the genetic material such as DNA and therefore be the reason for mutations). According to toluene msds when toluene is applied to the skin it can cause mild to moderate irritation. When toluene gets in contact with the eyes the person has a burning feeling which causes irritations and are the reason for diffirent eye clinical symptoms like conjunctivitis, corneal edema and abrasions, blepharospasm. When inhaled the toluene causes cough and wheezing affecting and irritating the upper part of the respiratory tract. Such inhalation also harms the CNS (central nervous system) and be the reason for nausea, dizziness, sleepiness tremors, memory loss, insomnia, ataxia, hallucinations(one of the reasons it can be used as a drug), somnolence, tachycardia, high or low blood pressure, unconsciousness and coma.